Resigned Director: THE CITY OF LONDON INVESTMENT TRUST PLC - Active (   From: Jul-2003   To: Jun-2009  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: THE CITY OF LONDON EUROPEAN TRUST LIMITED - Active (   From: Jul-2003   To: Jun-2009  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: RYBAR LABORATORIES LIMITED - Active (   From: May-2000   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: CITY OF LONDON FINANCE COMPANY LIMITED(THE) - Active (   From: Jul-2003   To: Jun-2009  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: CITY OF LONDON INVESTMENTS LIMITED - Active (   From: Jul-2003   To: Jun-2009  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: MONMOUTH PHARMACEUTICALS LIMITED - Active (   From: Jan-2000   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SHIRE PHARMACEUTICALS LIMITED - Active (   From: Dec-1999   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SHIRE PHARMACEUTICAL DEVELOPMENT LIMITED - Active - Proposal to Strike off (   From: Dec-1999   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: THE ENDOCRINE CENTRE LIMITED - Active (   From: Dec-1999   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SHIRE PHARMACEUTICALS GROUP - Dissolved (   From: Oct-2008   To: Apr-2013  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SPARKLEFLAME LIMITED - Active - Proposal to Strike off (   From: Dec-1999   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SHIRE HOLDINGS EUROPE LIMITED - Dissolved (   From: Dec-1999   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SHIRE INVESTMENTS & FINANCE (U.K.) COMPANY - Liquidation (   From: Dec-2001   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SHIRE PHARMACEUTICALS SERVICES LIMITED - Active - Proposal to Strike off (   From: Apr-2002   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SHIRE HOLDINGS UK LIMITED - Dissolved (   From: Feb-2003   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SHIRE EUROPE FINANCE - Active - Proposal to Strike off (   From: Aug-2004   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SHIRE GLOBAL FINANCE - Dissolved (   From: Apr-2005   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SHIRE BIOPHARMACEUTICALS HOLDINGS - Active - Proposal to Strike off (   From: Sep-2005   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SHIRE UK INVESTMENTS LIMITED - Active - Proposal to Strike off (   From: Sep-2005   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SHIRE HOLDINGS UK CANADA LIMITED - Active - Proposal to Strike off (   From: Oct-2006   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SHIRE EUROPE LIMITED - Active - Proposal to Strike off (   From: Apr-2008   To: Jun-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SHIRE JERSEY LIMITED - Converted / closed (   From: Jun-2007   To: Sep-2008  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP

Resigned Director: SHIRE PHARMACEUTICALS INVESTMENTS 2007 - Active (   From: Dec-2007   To: Nov-2007  )

Address: HAMPSHIRE INTERNATIONAL BUSINESS, PARK CHINEHAM, BASINGSTOKE, HAMPSHIRE, RG24 8EP