Resigned Director: 16 WEDDERBURN ROAD (MANAGEMENT) LIMITED - Active (   From: Feb-2000   To: Jun-2008  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU

Resigned Director: MVM (GP) LIMITED - Dissolved (   From: Dec-2000   To: Jul-2006  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU

Resigned Director: MVM LIMITED - Dissolved (   From: Feb-2000   To: Dec-2005  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU

Resigned Director: MVM LIMITED - Active (   From: Dec-2000   To: Jul-2006  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU

Resigned Director: PULMAGEN THERAPEUTICS (SYNERGY) LIMITED - Active - Proposal to Strike off (   From: Aug-2000   To: Aug-2006  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU

Current Director: PATHFINDER BIOPHARMACEUTICALS LIMITED - Dissolved (   From: Apr-1999  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU

Resigned Director: DOMANTIS LIMITED - Active (   From: Jul-2000   To: Sep-2006  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU

Resigned Director: ARDANA BIOSCIENCE LIMITED - Dissolved (   From: Jul-2000   To: May-2004  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU

Resigned Director: ETIOLOGICS LIMITED - Active - Proposal to Strike off (   From: Feb-2001   To: Oct-2004  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU

Resigned Secretary: MVM (CIP) (NO.2) LIMITED - Dissolved (   From: Mar-2002   To: Apr-2003  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU

Resigned Director: MVM (CIP) (NO.2) LIMITED - Dissolved (   From: Mar-2002   To: Jul-2006  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU

Resigned Secretary: MVM (GP) (NO.2) LIMITED - Dissolved (   From: Mar-2002   To: Apr-2003  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU

Resigned Director: MVM (GP) (NO.2) LIMITED - Dissolved (   From: Mar-2002   To: Jul-2006  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU

Resigned Director: XENTION LIMITED - Active (   From: Aug-2002   To: Sep-2006  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU

Resigned Director: ARDANA PLC - Dissolved (   From: May-2004   To: Mar-2005  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU

Resigned designated LLP Member: MVM PARTNERS LLP - Active (   From: Feb-2005   To: Oct-2005  )

Address: C/O MVM LIFE SCIENCE PARTNERS LLP, 1ST FLOOR, 6 HENRIETTA STREET, LONDON, WC2E 8PU