Resigned Secretary: PRELUDE VENTURES LIMITED - Dissolved (   From: Aug-1998   To: Jul-2001  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: PRELUDE TECHNOLOGY TRUSTEE LIMITED - Dissolved (   From: Aug-1998   To: Jul-2001  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: PRELUDE TECHNOLOGY INVESTMENT HOLDINGS LIMITED - Dissolved (   From: Aug-1998   To: Jul-2001  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: PRELUDE TECHNOLOGY LIMITED - Dissolved (   From: Aug-1998   To: Jul-2001  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: PRELUDE TECHNOLOGY II LIMITED - Dissolved (   From: Aug-1998   To: Jul-2001  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: ATM INVESTMENTS LIMITED - Dissolved (   From: Feb-1997   To: Apr-2003  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: ATM GLOBAL INVESTMENTS LIMITED - Dissolved (   From: Feb-1997   To: Apr-2003  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: ADVANCED TECHNOLOGY MANAGEMENT LIMITED - Dissolved (   From: Feb-1997   To: Apr-2003  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Current Secretary: ALIZYME THERAPEUTICS LIMITED - Liquidation (   From: Sep-2008  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: ACAMBIS RESEARCH LIMITED - Active - Proposal to Strike off (   From: Oct-1995   To: Feb-1998  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: SANOFI PASTEUR HOLDING LIMITED - Active - Proposal to Strike off (   From: Oct-1995   To: Feb-1998  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: ACAMBIS (UK) LIMITED - Dissolved (   From: Oct-1995   To: Feb-1998  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Current Director: HIGHLY STRUNG LIMITED - Active (   From: Feb-1995  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: UNNAMED LIMITED - Active (   From: Apr-1995   To: Oct-2018  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Current Secretary: ALIZYME PLC - Liquidation (   From: Sep-2008  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: AMURA LIMITED - Dissolved (   From: Apr-1997   To: Apr-1998  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: PRELUDE TRUST PLC - Dissolved (   From: Aug-1998   To: Aug-2001  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: ESPRIT CAPITAL MANAGEMENT LIMITED - Active - Proposal to Strike off (   From: Aug-1998   To: Jul-2001  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: E3 BIOTECH LIMITED - Dissolved (   From: Jan-2003   To: Apr-2003  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: AVLAR LIMITED - Active (   From: Apr-2001   To: Apr-2003  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Director: AVLAR LIMITED - Active (   From: Apr-2001   To: Apr-2003  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Director: AVLAR I (GENERAL PARTNER) LIMITED - Dissolved (   From: Jun-2001   To: Apr-2003  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Director: AVLAR I (CARRIED INTEREST PARTNER) LIMITED - Dissolved (   From: Jun-2001   To: Apr-2003  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Current Director: QUANTUM HEALTHCARE FUND MANAGER LIMITED - Dissolved (   From: Jul-2001  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Director: ASCRIP LIMITED - Dissolved (   From: Jun-2001   To: Apr-2003  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: AMURA THERAPEUTICS LIMITED - Dissolved (   From: Oct-2000   To: Dec-2000  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Current Secretary: MEDICAL VENTURES LIMITED - Dissolved (   From: Nov-2001  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: ALPHAMERIX LIMITED - Dissolved (   From: Aug-2003   To: Sep-2004  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Director: ALPHAMERIX LIMITED - Dissolved (   From: Aug-2003   To: Sep-2004  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Secretary: AVLAR BIOVENTURES SCOTTISH GP LIMITED - Dissolved (   From: Jun-2001   To: Apr-2003  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ

Resigned Director: AVLAR BIOVENTURES SCOTTISH GP LIMITED - Dissolved (   From: Jun-2001   To: Apr-2003  )

Address: 21 THE LINNETS, COTTENHAM, CAMBRIDGE, CAMBRIDGESHIRE, CB24 8XZ